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Skf-89,145

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Title: Skf-89,145  
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Subject: List of dopaminergic drugs, Nafadotride, CY-208,243, Ro10-5824, AS-8112
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Skf-89,145

SKF-89,145
Systematic (IUPAC) name
4-(6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridin-4-yl)benzene-1,2-diol
Clinical data
Legal status
?
Identifiers
ATC code ?
PubChem
Chemical data
Formula C14H15NO2S 
Mol. mass 261.339 g/mol
 YesY   

SKF-89,145 is a drug which acts as a dopamine agonist selective for the D1 subtype. The N-desmethyl derivative SKF-89,626 is also a selective D1 agonist with similar potency and selectivity to SKF 89,145.[1]

References

  1. ^ O'Boyle KM, Waddington JL (December 1987). "New substituted 1-phenyl-3-benzazepine analogues of SK&F 38393 and N-methyl-thienopyridine analogues of dihydroxynomifensine with selective affinity for the D-1 dopamine receptor in human post-mortem brain". Neuropharmacology 26 (12): 1807–10.  


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