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Title: Sib-1553a  
Author: World Heritage Encyclopedia
Language: English
Subject: TC-2216, AR-R17779, TC-1698, SSR-180,711, UB-165
Collection: Nicotinic Agonists, Nootropics, Phenols, Pyrrolidines, Thioethers
Publisher: World Heritage Encyclopedia


CAS number  YesY
Jmol-3D images Image 1
Molecular formula C13H19NOS
Molar mass 237.36 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)

SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.[1]


  1. ^ Schneider, JS (July 2003). "The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys". Journal of Pharmacology and Experimental Therapeutics 306 (1): 401–6.  

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