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2β-Propanoyl-3β-(2-naphthyl)-tropane

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Title: 2β-Propanoyl-3β-(2-naphthyl)-tropane  
Author: World Heritage Encyclopedia
Language: English
Subject: 2α-(Propanoyl)-3β-(2-(6-methoxynaphthyl))-tropane, FE-β-CPPIT, FP-β-CPPIT, 2β-Propanoyl-3β-(4-tolyl)-tropane, HDMP-28
Collection: Ketones, Naphthalenes, Serotonin-Norepinephrine-Dopamine Reuptake Inhibitors, Stimulants, Tropanes
Publisher: World Heritage Encyclopedia
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2β-Propanoyl-3β-(2-naphthyl)-tropane

2β-Propanoyl-3β-(2-naphthyl)-tropane
Systematic (IUPAC) name
2β-Propanoyl-3β-(2-naphthyl)-tropane
Pharmacokinetic data
Bioavailability high
Metabolism slow
Chemical data
Formula C21H25NO
Molecular mass 307.43 g/mol

2β-Propanoyl-3β-(2-naphthyl)-tropane or WF-23 is a cocaine analogue. It is claimed to be several hundred times more potent than cocaine at being serotonin-norepinephrine-dopamine reuptake inhibitor.[1]

As can be seen on pubmed, these acyl substituted phenyltropanes are highly potent MAT inhibitors and also have a very long half-life, spanning perhaps at least a few days.[2][3]

See also

References

  1. ^ U.S. Patent 6,008,227
  2. ^
  3. ^
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